Action of dinitrophenol and lanatoside C on the canine heart-lung preparation.
نویسندگان
چکیده
Dinitrophenol (DiSTP) induces failure of the canine heart-lung-preparation and increases specifically its Oj-consumption. Lanatoside C compensates this failure as long as the degree of dinitrophenol poisoning is moderate and the Oi-supply sufficiently ample. This cardiac glycoside does not influence the metabolic action of dinitrophenol, i.e. the increased Oj-cousumption, nor does it counteract the failure due to a large degree of dinitrophenol poisoning. From these findings the mechanism of action of Lanatoside C is discussed.
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ورودعنوان ژورنال:
- Circulation research
دوره 3 1 شماره
صفحات -
تاریخ انتشار 1955